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Gene Symbol |
KHDRBS3 |
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Aliases |
Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile |
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Entrez Gene ID |
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Gene Name |
KH RNA binding domain containing, signal transduction associated 3 |
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Chromosomal Location |
8q24.23 |
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HGNC ID |
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e!Ensembl
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Gene Ontology (GO)
| GO ID |
Ontology |
Function |
Evidence |
Reference |
| GO:0048024 |
Biological process |
Regulation of mRNA splicing, via spliceosome |
IBA |
21873635 |
| GO:0051259 |
Biological process |
Protein complex oligomerization |
IDA |
10332027, 10749975 |
| GO:0005634 |
Cellular component |
Nucleus |
IBA |
21873635 |
| GO:0005634 |
Cellular component |
Nucleus |
IMP |
10332027 |
| GO:0003723 |
Molecular function |
RNA binding |
HDA |
22681889 |
| GO:0003723 |
Molecular function |
RNA binding |
IBA |
21873635 |
| GO:0003723 |
Molecular function |
RNA binding |
IDA |
19561594 |
| GO:0005515 |
Molecular function |
Protein binding |
IPI |
10332027, 10749975, 16189514, 20195357, 25416956, 25910212, 26871637 |
| GO:0019904 |
Molecular function |
Protein domain specific binding |
IPI |
10332027, 10749975 |
| GO:0042802 |
Molecular function |
Identical protein binding |
IDA |
10332027, 10749975 |
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| Protein Information |
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Protein Name |
KH domain-containing, RNA-binding, signal transduction-associated protein 3, KH domain containing, RNA binding, signal transduction associated 3, RNA-binding protein T-Star, Sam68-like phosphotyrosine protein, T-STAR, sam68-like mammalian protein 2 |
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Function |
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UniProt |
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PDB |
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Associated Diseases
| Disease group | Disease Name | References |
| Endocrine System Diseases |
| PCOS |
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| Neoplasms |
| Breast Cancer |
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| Medulloblastoma |
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References |
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| PubMed ID |
Associated gene/s |
Associated condition |
Genetic Mutation |
Diagnostic Criteria |
Association with PCOS |
Ethnicity |
Conclusion |
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LHCGR, THADA, FSHR, YAP1, RAB5B and TOX3 |
hyperandrogenemia, menstruation number/year and polycystic ovary morphology |
rs10505648 |
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Direct
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862 women with PCOS and 860 controls in the Korean population |
The GRS was higher in women with PCOS than in controls (8.8 versus 8.2, P < 0.01) and was significantly associated with PCOS after adjusting for age and BMI |
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