Polycystic ovary syndrome (PCOS) is a very common endocrine disorder reported in women worldwide and is one of the major causes of female subfertility/infertility.  Numerous genes, SNPs and diseases are known to be associated with PCOS.

PCOSKB is a manually curated knowledgebase on PCOS. PCOS-related information available through scientific literature is cross-linked with molecular, biochemical and clinical databases. Information on associated genes, SNPs, diseases, gene ontologies and pathways along with supporting reference literature is collated and integrated in PCOSKB. Various tools are embedded in the database such as Comorbidity analysis for estimating the risk of diseases to co-occur with PCOS; Network analysis for identifying enriched pathways and hub genes and Venn analysis for finding common and unique genes, pathways and ontologies.

The Help page provides information on how to navigate the database and use its various resources.


Sharma, M., Barai, R.S., Kundu, I., Bhaye S., Pokar K., Idicula-Thomas S. PCOSKBR2: a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome. Sci Rep 10, 14738 (2020). doi: 10.1038/s41598-020-71418-8

Jeseph S, Barai RS, Bhujbalrao R, Idicula-Thomas S. PCOSKB: A KnowledgeBase on genes, diseases, ontology terms and biochemical pathways associated with PolyCystic Ovary Syndrome. Nucl. Acids Res. (2015) doi: 10.1093/nar/gkv1146.

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