ENHO: Polycystic Ovarian Syndrome Database

ENHO

Gene Information
 
Gene Symbol
ENHO
 
Aliases
C9orf165, UNQ470
 
Entrez Gene ID
 
Gene Name
Energy homeostasis associated
 
Chromosomal Location
9p13.3
 
HGNC ID
  e!Ensembl
Gene
Transcript  
Protein
Protein Information
 
Protein Name
Adropin, GAAI470, energy homeostasis-associated protein
 
Function
Involved in the regulation of glucose homeostasis and lipid metabolism.
 
UniProt
Interactions
 
STRING MINT IntAct
ENSP00000358165 P12314 P12314
    View interactions
     

Associated Diseases

Disease groupDisease NameReferences
Endocrine System Diseases
PCOS
Neoplasms
Breast Cancer
References
 
 
PubMed ID Associated gene/s Associated condition Genetic Mutation Diagnostic Criteria Association with PCOS Ethnicity Conclusion
 
PCOS 
 
 ROTTERDAM CRITERIA 
Related 
60 PCOS AND 60 CONTROL 
 Our findings suggest a probable involvement of adropin both in human metabolism and in the pathophysiology of PCOS. 
TNFA,  
PCOS, INSULIN SENSISTIVITY, ovulatory dysfunction, biochemical (elevated androgens) and Clinical (hirsutism and/or acne) hyperandrogenism 
 
 2003 Rotterdam consensus criteria 
Related 
152 women with PCOS and 152 age- and body mass index-matched controls without PCOS  
 Serum adropin levels are significantly decreased in PCOS and are inversely associated with TNF-?. Further dissection of the nature of this association can open new therapeutic options for metabolic diseases. 
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