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Gene Symbol |
MCF2L2 |
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Aliases |
ARHGEF22 |
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Entrez Gene ID |
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Gene Name |
MCF.2 cell line derived transforming sequence-like 2 |
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Chromosomal Location |
3q27.1 |
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HGNC ID |
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e!Ensembl
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SNPs
| SNP Id |
Upstream Sequence |
SNP |
Downstream Sequence |
Functional Significance |
References |
| rs35368790 |
AAATAAGTTTATTTCCCCCCGAGGA |
C/G |
TCTGCTGGTATAACAGATGAGAGAT
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|
19648752 | |
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| Protein Information |
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Protein Name |
Probable guanine nucleotide exchange factor MCF2L2, MCF2-transforming sequence-like protein 2, dbs-related Rho family guanine nucleotide exchange factor |
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Function |
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Probably functions as a guanine nucleotide exchange factor. |
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UniProt |
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Interactions |
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| STRING |
MINT |
IntAct |
| ENSP00000451828 |
P31749 |
P31749 |
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View interactions
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Associated Diseases
| Disease group | Disease Name | References |
| Endocrine System Diseases |
| PCOS |
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| Neoplasms |
| Colorectal Cancer |
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References |
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| PubMed ID |
Associated gene/s |
Associated condition |
Genetic Mutation |
Diagnostic Criteria |
Association with PCOS |
Ethnicity |
Conclusion |
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SNP variants-rs35368790(associated),[ rs35069869 and rs684846(not associated)] of gene |
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Related
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Chinese population |
These results suggest that the genetic polymorphisms within MCF2L2 are likely to confer an increased susceptibility to PCOS in the Chinese population. |
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