MEP1A: Polycystic Ovarian Syndrome Database

Gene Information

Gene Symbol

MEP1A

Aliases

PPHA

Entrez Gene ID

4224

Gene Name

Meprin A subunit alpha

Chromosomal Location

6p12.3

HGNC ID

HGNC:7015

e!Ensembl

Gene	ENSG00000112818
Transcript	ENST00000230588, ENST00000611727
Protein	ENSP00000230588, ENSP00000480465

SNPs

SNP Id	Upstream Sequence	SNP	Downstream Sequence	Functional Significance	References
rs17468190	CGATTACTACGCCTACAGCCCTGTGC	A/G	GGAGCGGGACGCCCACTCCGTCCTC	Intron variant,utr variant 3 prime	24388959

Gene Ontology (GO)

Show/Hide all(7 )

GO ID	Ontology	Function	Evidence	Reference
GO:0005615	Cellular component	Extracellular space	TAS	8262185
GO:0005887	Cellular component	Integral component of plasma membrane	TAS	8262185
GO:0017090	Cellular component	Meprin A complex	IBA	21873635
GO:0017090	Cellular component	Meprin A complex	IDA	9288916
GO:0070062	Cellular component	Extracellular exosome	HDA	11487543
GO:0004222	Molecular function	Metalloendopeptidase activity	IBA	21873635
GO:0005515	Molecular function	Protein binding	IPI	9288916, 23123160

Protein Information

Protein Name

Meprin A subunit alpha, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha, PABA peptide hydrolase, PPH alpha, bA268F1.1 (meprin A alpha (PABA peptide hydrolase)), endopeptidase-2, meprin A, alpha (PABA peptide hydrolase)

Function

UniProt

Q16819

Pfam

Pfam Accession	Pfam ID
PF01400	Astacin
PF00008	EGF
PF00629	MAM