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Gene Symbol |
MUC5AC |
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Aliases |
MUC5, TBM, leB, mucin |
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Entrez Gene ID |
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Gene Name |
Mucin 5AC, oligomeric mucus/gel-forming |
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Chromosomal Location |
11p15.5 |
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HGNC ID |
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e!Ensembl
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| Protein Information |
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Protein Name |
Mucin-5AC, gastric mucin, lewis B blood group antigen, major airway glycoprotein, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, tracheobronchial mucin |
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Function |
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UniProt |
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PDB |
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Interactions |
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| STRING |
MINT |
IntAct |
| ENSP00000295927 |
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P26022 |
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View interactions
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Associated Diseases
| Disease group | Disease Name | References |
| Blood Disorders |
| Von Willebrand Disease |
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| Cardiovascular Diseases |
| Sick Sinus Syndrome |
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| Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| Cystic Fibrosis |
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| Digestive System Diseases |
| Gastritis |
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| Pancreatitis |
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| Hepatolithiasis |
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| Gastroesophageal reflux disease |
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| Ear Or Mastoid Diseases |
| Otitis |
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| Endocrine System Diseases |
| PCOS |
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| Eye Diseases |
| Dry Eye Syndromes |
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| Disorder of eye |
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| Immune System Diseases |
| Allergic rhinitis |
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| Musculoskeletal Diseases |
| Necrosis |
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| Neoplasms |
| Lung Cancer |
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| Colorectal Cancer |
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| Bile Duct Cancer |
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| Pancreatic Neoplasm |
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| Adenocarcinoma |
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| Pulmonary Adenocarcinoma |
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| Neoplasms |
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| Gastrointestinal Cancer |
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| Pancreatic Ductal Adenocarcinoma |
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| Gastric Cancer |
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| Colonic Neoplasms |
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| Pancreatic Cyst |
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| Ovarian Cancer |
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| Cholangiocarcinoma |
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| Rectal Neoplasms |
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| Intrahepatic Cholangiocarcinoma |
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| Breast Cancer |
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| Intraductal Carcinoma |
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| Adenocarcinoma Of Pancreas |
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| Carcinoma |
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| Squamous Cell Carcinoma |
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| Ductal Carcinoma |
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| Ovarian Adenocarcinoma |
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| Bladder Cancer |
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| Nutritional and Metabolic Diseases |
| Hyperinsulinism |
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| Psychiatric/Brain disorders |
| Behavior Disorders |
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| Renal Disorder |
| Nephrolithiasis |
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| Respiratory Tract Diseases |
| Lung Diseases |
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| Chronic Bronchitis |
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| Airway Obstruction |
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| Asthma |
29031476, 28716644, 29676620, 29129801, 29997053, 30628655, 26549244, 28942146, 29382534, 27183390, 27553766, 26161982, 27246785, 26057128, 30552067, 26318254 |
| Chronic Obstructive Pulmonary Disease |
30727993, 29158154, 25809288, 27912076, 26882402, 28602698, 25700379, 25776934, 27036871, 28894207, 26079889, 29496167, 29892905 |
| Rhinitis |
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| Respiratory Tract Infections |
30061200, 29767240, 28205598, 29998888, 27911216, 26980390, 26062017, 27184164, 30907357, 28729052, 27423012, 26245530, 29349683, 29688024 |
| Respiratory Distress Syndrome |
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| Bronchiectasis |
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| Pulmonary Fibrosis |
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| Pneumonia |
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References |
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| PubMed ID |
Associated gene/s |
Associated condition |
Genetic Mutation |
Diagnostic Criteria |
Association with PCOS |
Ethnicity |
Conclusion |
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MUC1 |
Ocular symptomatology |
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Related
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Patients with PCOS had a significant reduction of the tear film BUT accompanied by a significant increase in goblet cell number and conjunctival MUC5AC messenger ribonucleic acid expression compared with both PCO patients and healthy subjects. |
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