RETN: Polycystic Ovarian Syndrome Database

Interactions

STRING	MINT	IntAct
ENSP00000397908		Q14693

View interactions

Associated Diseases

Show/Hide all(5 )

Disease group	Disease Name	References
Cardiovascular Diseases
	Myocardial Failure	26670611
	Heart Failure	26670611
Endocrine System Diseases
Endocrine System Diseases	PCOS	30062709, 19821101
Nutritional and Metabolic Diseases
Nutritional and Metabolic Diseases	Metabolic Syndrome X	18328350
Psychiatric/Brain disorders
Psychiatric/Brain disorders	Obstructive Sleep Apnea	31013606
Renal Disorder
	Kidney Failure	19539174
	Kidney Insufficiency	22421264

References

Show/Hide all(20)

PubMed ID	Associated gene/s	Associated condition	Genetic Mutation	Diagnostic Criteria	Association with PCOS	Ethnicity	Conclusion
14688155	insulin resistance			PCOS was defined by clinical, laboratory and ultrasound criteria.	Related	17 PCOS and 10 Control	Overexpression of the resistin gene in adipocytes may be a local determinant factor in the pathogenesis of PCOS
18937712	leptin and ghrelin				Related	28 PCOS and 19 control
23199261	Adiponectin and Leptin				Related	87 PCOS and 67 Control
21756250					Related	281 womens
21557697	IR				Related		Plasma resistin does not correlate with normal weight PCOS or IR.
21063848	Serum Adiponectin				Related	46 PCOS	Adiponectin and resistin might play important roles in the pathogenesis of IR in PCOS patients
20889251	Serum Adiponectin	Hyperandrogensim			Related	41 PCOS and 16 Control	Resistin concentration did not differ in normal weight and obese PCOS compared to control subjects
20148738	Adipocytokine				Related	31 PCOS and 25 Control	resistin levels may not be candidate to play a role in pathogenesis of PCOS without insulin resistance or obesity
19821101	Insulin resistance				Related	35 PCOS and 40 controls	resistin might be involved in the pathogenesis of insulin resistance of PCOS.
19639497	Adiponectin				Related	22 PCOS and 16 controls
19544118	Adiponectin				Related	117 PCOS and 380 controls	RETN G/G at -420 genotype is associated with PCOS in Japanese women
15886251	17alpha-hydroxylase			Women with PCOS were identified based on a history of oligo/amenorrhea, hirsutism or hyperandrogenemia, and typical morphological appearance of polycystic ovaries (normal or enlarged ovarian volume with multiple subcapsular cysts <8 mm in diameter) with n	Related	45 PCOS and 74 Control	Abnormal resistin secretion in PCOS may play a role in causing ovarian hyperandrogenism
15862282	Adiponectin				Related	19 PCOS	strong negative correlation between serum adiponectin and resistin, despite the lack of direct correlation with the indices of IR
15513972				Rotterdam criteria	Related	21 PCOS and 18 Control	Resistin is unlikely to be a major determining factor in the growth and maturation of oocytes during IVF-stimulated cycles in PCOS
14967374				Women with PCOS presented at our gynecologic endocrinology infirmary with at least one of the following signs: oligomenorrhea, a fertility problem, hirsutism, acne, and male-pattern alopecia.	Related	35 PCOS, 35 PCOS and 20 control	Resistin is unlikely to be a major determining factor of PCOS-associated insulin resistance
19408174	Adiponectin				Related	76 PCOS and 42 Control	resistin levels were independently associated with insulin resistance and BMI in PCOS patients
18504045	insulin resistance				Related	50 PCOS	Serum levels of intact proinsulin, resistin, or adiponectin were not detectors of IR in individual young women with PCOS
17653882		infertility			Related	44 PCOS	Serum resistin levels might be a good predictor of ovarian response in infertile women without PCOS during IVF
17208941				Rotterdam criteria	Related	12 PCOS	Resistin activity may be actively involved in the pathogenesis of PCOS
16130192	FF			Adams et al. 1986	Related	20 PCOS and 20 Control	resistin does not have correlation with the hormonal and metabolic parameters as well as the outcomes of IVF