SLC12A8: Polycystic Ovarian Syndrome Database

Gene Information

Gene Symbol

SLC12A8

Aliases

CCC9

Entrez Gene ID

84561

Gene Name

Solute carrier family 12 member 8

Chromosomal Location

3q21.2

HGNC ID

HGNC:15595

Summary

This gene is thought to be a candidate for psoriasis susceptibility. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2010]

RefSeq DNA

NG_027706.1

RefSeq mRNA

NM_024628.5, NM_001195483.1

e!Ensembl

Gene	ENSG00000221955
Transcript	ENST00000430155, ENST00000393469, ENST00000473262, ENST00000469902, ENST00000479826, ENST00000462437
Protein	ENSP00000415713, ENSP00000377112, ENSP00000419424, ENSP00000418783, ENSP00000420197, ENSP00000418636

Gene Ontology (GO)

Show/Hide all(6 )

GO ID	Ontology	Function	Evidence	Reference
GO:0006884	Biological process	Cell volume homeostasis	IBA	21873635
GO:0055064	Biological process	Chloride ion homeostasis	IBA	21873635
GO:0055075	Biological process	Potassium ion homeostasis	IBA	21873635
GO:1902476	Biological process	Chloride transmembrane transport	IBA	21873635
GO:1990573	Biological process	Potassium ion import across plasma membrane	IBA	21873635
GO:0015379	Molecular function	Potassium:chloride symporter activity	IBA	21873635

Protein Information

Protein Name

Solute carrier family 12 member 8, cation-chloride cotransporter 9, solute carrier family 12 (sodium/potassium/chloride transporters), member 8

Function

Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation.

Refseq Proteins

NP_078904.3, NP_001182412.1

UniProt

A0AV02